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The Nonnekens research laboratory

Research

Our mission is to enhance the understanding of the molecular and cellular impacts of radioactive anti-cancer agents, leveraging this knowledge to refine existing treatments and innovate new ones. Our ultimate goal is to contribute to the improved care of patients with metastasized diseases. 

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Our research is centered around three primary themes: 

  • Cellular effects of radionuclide in tumor cells: Investigating the impact of radionuclide therapy on tumor cells at the cellular level. 

  • Radiobiology and dosimetry of different radiation qualities: Studying the radiobiological aspects and dosimetry of various radiation qualities to gain insights into their effects. 

  • Radiosensitization for improved radionuclide therapy outcome: Exploring strategies to enhance radiosensitivity, with the aim of improving outcomes in radionuclide therapy. 

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Our research spans multiple levels, encompassing studies conducted at the cellular and animal level, as well as utilizing computational models and patient-based research. This diverse approach enables us to seamlessly translate our discoveries from laboratory experimentation to real-world applications. 

The Erasmus MC

Situated within the Departments of Molecular Genetics and Radiology & Nuclear Medicine at Erasmus University Medical Center in Rotterdam, our laboratory is strategically positioned at the largest academic hospital in the Netherlands. This institution facilitates high-level research, empowering us to conduct groundbreaking studies at the forefront of scientific innovation.  

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